Sweet N Low Side Effects Splenda/Equal/Sweet N Low?

Splenda/Equal/Sweet n Low? - sweet n low side effects

Ok. So most days, we have about 30 packets Splenda for low cost and 12 ounces diet soda. If you use this artificial sweetener a lot, there is really no calories? Do you have a single package really only 0 calories? Moreover, there are side effects to replace large eat so much sugar?
Thx!